DDX3X and cancer: Another potential connection involving TRA2A is that both it and FOXQ1 activity have been implicated during the cancer progressing epithelial to mesenchymal transition (EMT) [33–35], as has the DEAD (Asp-Glu-Ala-Asp)-box helicase 3X (DDX3X) protein that was also found to bind in the same region of FOXQ1 mRNA [36].