A potentially practical prognostic opportunity was proposed by other cellular and biochemical factors, that are not in routine clinical practice, such as the sustained elevated production of IL-6 [2, 4, 17, 23, 24, 26, 27, 29–31, 39], IL-1, IL-2R, IL-8, IL-10 [2, 17, 40] and some other blood circulating factors, whose early evaluation anticipated disease progression and duration of hospital stay of COVID-19 patients [41]. The gene discussed is IL6; the disease is COVID-19.