Particularly, significant upsurges were observed in IL17A, TNF-α, IL6, IL12, Eotaxin, CXCL1, IFN-γ, MCP-1, and IL9 in the plasma concentrations of mice with established CRC upon administration of F. nucleatum as compared to that upon PBS treatment, suggesting an inflammation promoting role of F. nucleatum. The gene discussed is CCL2; the disease is colorectal carcinoma.