We started with an NDM-model diabetic-mouse line previously constructed by the Nichols’ group, which contained an inducible mutant mKir6.2 transgene in the Rosa26 locus (PdxCreERT2; Rosa26lsl-Kcnj11), hereafter referred to as Rosa26mKir6.2NDM (Remedi et al., 2009). Here, KCNJ11 is linked to neonatal diabetes mellitus.