SCN1A and Dravet syndrome: Work in preclinical experimental mouse models of DS (Scn1a+/- mice) demonstrates temporal lobe-onset seizures (Liautard et al., 2013) and prominent activation of hippocampal DG during temperature-sensitive seizures (Dutton et al., 2017), suggesting involvement of hippocampus in seizure generation in Scn1a+/- mice.