Positive PD‐L1 IHC expression (≥5% positive cells in the cores) was found in 44/125 (35.2%) of the HGSOC primary, whereas in 65/125 (52%) of the metastatic lesions Positive PD‐L1 IHC expression in the primary OC lesions was associated with high stage (lymph node metastasis), whereas in the metastatic peritoneal lesions with high grade and ki‐67 status. Here, CD274 is linked to metastatic malignant neoplasm in the lymph nodes.