IL10 and retinitis pigmentosa 1: Interleukin (IL)-10 mRNA expression in freshly isolated PBMCs in RP patients was significantly higher than that in healthy individuals.[6] IL10 is a major regulatory T (Treg)-related anti-inflammatory cytokine.[7] In contrast to the results of freshly isolated PBMCs, in 6-hour-cultured PBMCs with mitogen stimulation, IL10 mRNA expression decreased significantly in RP patients compared with that in healthy individuals.[6]