IL6 and retinitis pigmentosa 1: Reduced IL10 production is associated with IFNγ production by effector T cells[21] and IL1β and IL6 release from monocytes/macrophages,[38] which promotes damage to chondrocytes.[39] MMP3 secreted by chondrocytes aggravates chondritis in an autocrine manner.[25] These molecules may subsequently be related to severe chondritis in patients with RP.