Statistically significant differences were found between CAN‐positive and CAN‐negative patients (p < .05) in the following variables: diastolic blood pressure (p < .001), albumin/creatinine ratio (p = .002), UENS score (p = .0228), MNSIQ score (p = .0018), and MNSIE score (p = .0025). Here, ALB is linked to Crouzon syndrome-acanthosis nigricans syndrome.