Indeed, autoimmune processes could play a determinant role in the pathophysiology of narcolepsy;6, 45, 46 H1N1 influenza or streptococcus infections could stimulate autoreactive T‐cells or B‐cells, then an enhanced permeability of the blood–brain barrier provoked by fever and inflammation could facilitate autoreactive T‐cell transfer into the brain that may induce a transient autoimmune attack of hypocretin cells.47 The gene discussed is HCRT; the disease is narcolepsy.