The percentage of lower airway pDCs expressing FcεRIα was significantly increased in asthma patients (23.6 [14.08, 25.3]) compared to healthy controls (5.44 [4.26 18.89]) at baseline (p = .047), consistent with the elevated expression observed in peripheral blood,23, 24 with a trend towards increased expression in asthma (17.9 [11.2, 24.7]) at D3 post infection compared to healthy controls (4.15 [0.76, 7.70]) (p = .068) (Figure 6D). Here, FCER1A is linked to infection.