In order to further study the possible role and mechanism of fibrinogen α chain in the occurrence and development of NSCLC, string PPI network database was used to analyze and predict the related proteins (ApoA1, ITIH2, ALB, AHSG, HRG, FGB, FGG, F2, F13B, and SERPINC1) (Figure 7). The gene discussed is SERPINC1; the disease is non-small cell lung carcinoma.