In order to further study the possible role and mechanism of fibrinogen α chain in the occurrence and development of NSCLC, string PPI network database was used to analyze and predict the related proteins (ApoA1, ITIH2, ALB, AHSG, HRG, FGB, FGG, F2, F13B, and SERPINC1) (Figure 7). This evidence concerns the gene F2 and non-small cell lung carcinoma.