Among other subtypes, subtype 1 is enriched for oligodendrogliomas (p < 1.0 × 10−5), mutations in the TERT promoter and high expression of TERT (Tukey HSD test, p < 0.05 for all pairwise comparisons), high tumor purity (Tukey HSD test, p < 0.05 for all pairwise comparisons), 1p/9q codeletion, and mutations in CIC, a known tumor suppressor. The gene discussed is TERT; the disease is neoplasm.