PTK2 and neoplasm: Immunoblot analysis of xenograft tumor tissues showed that Ab27 decreased the phosphorylation of FAK (moderately), c-Src (moderately), p27Kip1, and STAT3, and the expression of BMI1, whereas sorafenib moderately decreased the phosphorylation of FAK, c-Src, p27Kip1, and STAT3 and the expression of BMI1 (Figure 2C).