Immunoblot analysis of tumor tissues revealed that Ab27 decreased the phosphorylation of p27Kip1 and STAT3 and the expression of p27Kip1 and BMI1, but had a less substantial effect on the phosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2) (Figure S3E). This evidence concerns the gene BMI1 and neoplasm.