In addition, as shown in Supplementary figure 2B, in a melanoma intratumor heterogeneity dataset [76], 24 out of 29 m6A-RMRs (83%) (except RBM15B, IGF2BP1, IGF2BP3, HNRNPA2B1, and HNRNPC) were in the medium to high expression levels in cancer-associated fibroblasts (CAF) of melanoma. The gene discussed is HNRNPC; the disease is melanoma.