When comparing three groups of acute inflammations, sepsis plus ARDS shared three upregulated m6A-RMRs such as writers WTAP, PCIF1, and reader YTHDF3 with sepsis plus shock; sepsis plus ARDS shared upregulation of one RNA binding protein IGF2BP2 with trauma, and sepsis plus shock shared one RNA binding protein IGF2BP3 with trauma. Here, WTAP is linked to acute respiratory distress syndrome.