ITGA5 and cancer: We also identified ITGA5 (target gene of miR-28-x, miR-411-y, ssc-miR-1285), ITGA6, and ITGAL (target gene of ssc-miR-326, ssc-miR-1, ssc-miR-9860-5p) as being significantly differentially expressed (DE) between the normoxic and hypoxic groups, and these are downstream genes related to the ECM, proteoglycans in cancer and focal adhesion pathways.