LDHA (the target genes of ssc-miR-429, ssc-miR-141, and miR-101-y) was expressed at a higher level in the hypoxia (TL and LL) groups than in the normoxia (TN and LN) groups and was significantly different in the TN and TL groups; this gene could be regulated by HIF-1α, and increased LDH expression may have promoted the accumulation of lactic acid in anaerobic glycolysis under the condition of hypoxia and further increased apoptosis, leading to numerous lung diseases in the hypoxic groups (TL and LL) (43, 57, 58). Here, LDHA is linked to lung disorder.