Among the predicted miRNAs and mRNAs, ADAM9, CAND1, CNOT8, DACH1, EIF3J, RAP2C, RB1, and VCAN were found to be deregulated in breast cancer with lymph node metastasis compared with those without lymph node metastasis (Figures 5A-H). The gene discussed is CNOT8; the disease is metastatic malignant neoplasm in the lymph nodes.