By using the five genes screened and corresponding coefficients to construct a risk score feature, and the risk score formula was as follows: Risk score = (−0.0318 × the expression of NLRP6) + (−0.0499 × the expression of GSDMA) + (−0.0234 × the expression of IL-6) + (−0.0114 × the expression of CASP1) + (−0.3714 × the expression of CASP9), In our risk score, the five selected genes were tumor-suppressor genes. The gene discussed is CASP9; the disease is neoplasm.