Enriched KEGG pathways were involved in neuroactive ligand-receptor interaction; cardiac muscle contraction; vascular smooth muscle contraction; the cyclic guanosine monophosphate (cGMP)-protein kinase G (PKG) signaling pathway; the cyclic adenosine 3', 5'-monophosphate (cAMP) signaling pathway; adrenergic signaling in cardiomyocytes; cardiac muscle contraction; dilated cardiomyopathy; insulin secretion; and salivary secretion. The gene discussed is PRKG1; the disease is dilated cardiomyopathy.