SFTPD and acute respiratory distress syndrome: Conversely, the rise in circulating SP-D levels between D1 and D5 and between D1 and D14 was, respectively, associated with reduced risk of ARDS onset by one-tenth and one-fifth (D1 to D5 OR was 0.106 [0.03–0.326]; p < 0.001; D1 to D14 OR was 0.181 [0.051–0.59]; p =0.006) (Table 3).