Additionally, germ cell-specific (DEAD-box helicase 4), seminal vesicle-specific (Semenogelin 1), and prostate-specific (Transglutaminase 4) mRNAs in seminal plasma could be markers for identifying the presence of germ cells or the rough localization of complete obstructive azoospermia (Li et al., 2012). This evidence concerns the gene TGM4 and Azoospermia.