In our study, we systematically analyzed the expression level of ANXA2P2 in pan-carcinoma and relevant normal samples, indicating that ANXA2P2 was dramatically overexpressed in a variety of cancers compared with corresponding normal tissues, including ACC, BLCA, BRCA, CESC, CHOL, COAD, ESCA, GBM, KICH, KIRC, KIRP, LGG, LIHC, LUSC, OV, PAAD, SKCM, STAD, TGCT, THCA, UCEC, and UCS on the integrated correction data of TCGA and GTEx datasets. This evidence concerns the gene ANXA2P2 and carcinoma.