Based on the reads per kilobase of exon per million mapped reads (RPKM) value (p < 0.05) and log2(fold change) > 1, we choose 17 genes which were all significantly upregulated in pancreatic tissues from miR-301a−/−;Pdx1-Cre;KrasG12D mice and correlated with poor prognosis in patients with pancreatic cancer (Figure S5A). Here, PDX1 is linked to familial pancreatic carcinoma.