Although most previous studies reported that ULBP1 was related to recurrence-free survival, disease-free survival, or overall survival (OS) in different cancers (McGilvray et al., 2009; McGilvray et al., 2010; Mondelli, 2012; Chen et al., 2013; Maccalli et al., 2017), the relationship between ULBP1 and OS in COAD has not been reported yet. Here, ULBP1 is linked to colon adenocarcinoma.