The same group showed, in another study, that the coadministration of anti-VEGFR-2 CAR-T cells along with tumor-specific TCR transduced T cells (premelanosome (Pmel) TCR, tyrosinase-related-protein-1 (TRP-1) TCR, and tyrosinase-related-protein-2 (TRP2) TCR traduced T cells) resulted in a synergic anti-tumor effect and an extended tumor-free survival (TFS) of mice with metastatic melanoma tumors. The gene discussed is KDR; the disease is neoplasm.