Tumor endothelial marker 8 (TEM8), also known as anthrax receptor 1 (ANTRX1), is another cell membrane glycoprotein consistently overexpressed in the tumor vasculature and in many types of cancer, including breast (102), gastric (103),, skin (104), colon (105), and lung (106) cancers. The gene discussed is ANTXR1; the disease is cancer.