As shown in Fig. 7A, the expression of RFC2 was positively correlated with the TMB of 18 types of cancers, including LGG, BRCA, LUSC, ACC, LUAD, PRAD, KIRC, SKCM, KIRP, BLCA, STAD, LIHC, MESO, SARC, UCEC, HNSC, PAAD, and KICH, while its expression was negatively related with the TMB of THYM and ESCA. This evidence concerns the gene RFC2 and cancer.