AFP and cirrhosis of liver: The data revealed that hsa_circ_0001394 expression in preoperative blood was correlated with the AFP level (p = 0.0117), tumor differentiation (p = 0.0039), and vascular invasion (p = 0.0137), while there was no significant difference in age, sex, tumor size, liver cirrhosis, or hepatitis virus between the expression groups (p > 0.05) (Table 2).