Briefly, based on the results of STMN1 immunostaining on HCC specimens from 130 early HCC patients, the obtained expression levels of STMN1 were divided into three groups: (1) M0 group was defined as score of 0, based on detections with MVI negative (n = 51); (2) Mlow-risk group was defined as score of 1–2, based on detections with MVI positive of low-STMN1 expression (n = 45); (3) and Mhigh-risk group was defined as score of 3–4, based on detections with MVI positive of high-STMN1 expression (n = 34) (Fig. 4A, B). Here, STMN1 is linked to hepatocellular carcinoma.