CD4 and neoplasm: Logistic regression analysis of odds ratios for potential associated factors showed an association between the occurrence of MNTs and high tumor burden at baseline before the start of lymphodepletion, high levels of IL-6 at baseline, grade ≥2 CRS, incidence of ICANS, high CAR T-cell expansion and persistence, and high ALC (including absolute CD4+ T cells) on Days 14, 21, and 28 post cilta-cel infusion (Fig. 4).