Thirteen genes (BRCA1, BRIP1, ERCC4, EXO1, FANCD2, FANCG, FANCI, MAD2L2, NBN, PMS2, RAD51B, TXNRD1, XRCC2) were previously associated with platinum sensitivity/resistance and 21 genes are shown as regulating platinum sensitivity of cancer cells for the first time. The gene discussed is XRCC2; the disease is cancer.