Moreover, this was accompanied by a reduction in Aβ deposition and cognitive impairment, releasing the neuronal damage [80] It has been reported that Angelica Sinensis Shao Yao San reduced Aβ41-42 deposition in the brain of APP/PS1 mice and improved amyloidosis and neuronal degeneration in Alzheimer’s disease through a similar molecular mechanism [80]. Here, APP is linked to early-onset autosomal dominant Alzheimer disease.