PROM1 and hepatocellular carcinoma: The results showed that high expression of CD133 served as a significant independent prognostic factor for poor OS in HCC after TAE/TACE (HR, 2.013; 95% CI, 1.223–3.314; p = 0.006), as well as vascular invasion (HR, 1.821; 95% CI, 1.124–2.9.52; p = 0.015) and metastasis (HR, 2.033; 95% CI, 1.002–4.125, p = 0.049) (Table 5).