It has been demonstrated that T cytotoxic cells (CTLs) from patients with ITP have a higher rate of proliferation and a lower rate of apoptosis, a fact that leads to a higher amount of IL-2, IFN-γ, and IL-10 secreted by them; this secretion being responsible for lower CD4+CD25+Foxp3+ Treg cell levels and efficiency in patients with active disease [56,57,58,59,60,61]. This evidence concerns the gene IL10 and autoimmune thrombocytopenic purpura.