FAS and autoimmune thrombocytopenic purpura: The studies showing upregulation of interferon-γ, IL-2Rβ, perforin together with granzyme A, granzyme B, and Apo-1/Fas gene (the mediators of CTL induced apoptosis) are in favor of the T cell-mediated cytotoxicity relationship with platelet destruction in ITP [67].