Furthermore, CD74 immunohistochemical expression increased in higher-grade and late-stage metastatic invasive cancers compared to less aggressive and lower-grade cancers, as reported in thymic epithelial neoplasms [28], colorectal, gastric, and pancreatic cancers [29], and urothelial carcinoma of the bladder [17]. The gene discussed is CD74; the disease is pancreatic neoplasm.