It is possible that our results reflect this: although the link to the mTOR pathway is only by association with the effects of Fnip1, we did see up-regulation of Pik3 in IUGR-R compared to IUGR-L and a general indication of effects on the RAS pathway in Clusters C and D (heavier vs. lighter animals). The gene discussed is MTOR; the disease is fetal growth restriction.