However, Repin1 expression was also down-regulated in IUGR-R animals, which had a very similar adipocyte size distribution to that of IUGR-L animals, so it is not clear if whether Repin1 expression directly relates to adipocyte size in these animals or whether another factor modulates the effect in IUGR-R animals. This evidence concerns the gene REPIN1 and fetal growth restriction.