DRD2 and obesity disorder: After the initial conceptualization of RDS by Blum in 1995, Blum et al., using the Bayesian Theorem [34], found that carriers of the DRD2 A1 allele had a predictive value (PV) for any future RDS behaviors, such as substance use disorder (SUD), obesity, and shopping addiction, that reached 74.4% [34].