Third, because a single miRNA can target hundreds of mRNAs [37], miR-30a-3p expression was considered a candidate biomarker for EC carcinogenesis, such as through the targeting of E-cadherin [38] and cancer/testis antigen (CAGE) [31,39] by miR-30a-3p and promotion of cell cycle progression by miR-200b to regulate cyclin D1 [40]. This evidence concerns the gene CCND1 and cancer.