Moreover, no statistically significant differences were found in C3 [1.14 g/L (IQR 1.01–1.24 g/L) vs. 1.12 g/L (IQR 1–1.2 g/L); p > 0.05], C4 [0.2 g/L (IQR 0.16–0.23 g/L) vs. 0.2 g/L (IQR 0.15–0.27 g/L); p > 0.05], ESR [23 mm/h (IQR 13–37 mm/h) vs. 16 mm/h (IQR 10–26 mm/h); p > 0.05] and CRP [1900 mcg/L (IQR 1000–5200 mcg/L) vs. 1750 mcg/L (IQR 700–2600 mcg/L); p > 0.05] between SSc patients with ILD and SSc patients without ILD. Here, CRP is linked to interstitial lung disease.