These included the protein properdin (CFP, −2.0-fold), significantly downregulated in AF, and the proteins annexin A1 (ANXA1, +2.7-fold), annexin A2 (ANXA2, +4.0-fold), haptoglobin (HP, +3.9-fold), alpha-enolase (ENO1, +2.9-fold), vimentin (VIM, +4.1-fold), and alpha-1-acid glycoprotein 2 (ORM2, +2.4-fold), all significantly upregulated in AF. The gene discussed is ORM2; the disease is atrial fibrillation.