SMAD3 and adenomyosis: TGF-β2 and SMAD3 (Figure 3A,B) expression were upregulated in Adeno compared with Control sec-organoids (TGF-β2: 55.78 ± 20.26% vs. 14.45 ± 7.51%, p < 0.0001 and SMAD3: 33.95 ± 9.88% vs. 11.22 ± 7.51%, p < 0.0001), and gest-organoids (TGF-β2: 43.81 ± 12.22% vs. 1.41 ± 2.00%, p = 0.0003 and SMAD3: 28.81 ± 87.69% vs. 21.16 ± 11.44%, p = 0.3282) (Figure 3C,D), as observed in adenomyosis [32,37].