The KCa1.1 and KCa3.2 channels are the main calcium-activated potassium channels able to modulate directly chemotherapeutic-response in several cancers, including OC, glioblastoma, esophageal squamous carcinoma, melanoma, and osteosarcoma [33,34,47,48,49]. This evidence concerns the gene KCNMA1 and glioblastoma.