YWHAQ and cancer: There are seven well-recognized isoforms of 14-3-3 proteins, namely 14-3-3ζ, 14-3-3σ, 14-3-3β, 14-3-3ε, 14-3-3γ, 14-3-3η and 14-3-3τ/θ in various cancers, of which 14-3-3ε has been implicated in kidney, liver, squamous cell, breast and stomach cancers [40,41].