Among the total isolated CTCs, 30.57% were (CK+/TUB+CD45−), while the rest of the cells appeared with either low (35.97%) or negative (28.66%) tubulin expression (Figure 2c); 4.79% of the total isolated CTCs (only in advanced disease) belonged to (CK−/TUB+CD45−) phenotype and the frequency of these tumor cells was statistically different compared to all the other phenotypes (Figure 2c). The gene discussed is TUB; the disease is neoplasm.