Recently, Suzuki and colleagues identified NETs in the alveolar and interstitial lung space of mice undergoing bleomycin-induced lung fibrosis, which was suppressed by a pan-PAD inhibitor, demonstrating that Padi4 gene knockout in mice led to the alleviation of bleomycin-induced NETs and pulmonary fibrosis; this finding suggests that this pathway could be useful as a therapeutic target in the treatment of pulmonary fibrosis [60]. Here, PADI4 is linked to pulmonary fibrosis.