IGF1 and endometriosis: Arablou et al. study, conducted on 40 patients with endometriosis, have shown that the treatment of eutopic endometrial stromal cells and ectopic endometrial stromal cells with RSV can reduce the gene expression and production of insulin-like growth factor-1 (IGF-1), hepatocyte growth factor (HGF) and the gene expression of control endometrial stromal cells [61].