LR models suggested that MCI status, APOE4 status, corrected hippocampal volume (HV), [F18] fluorodeoxyglucose (FDG) PET SUVR, and CSF t-tau/p-tau were associated with fast AD progression, which was then used to construct nomograms where a specific point corresponds to each variable based on the beta coefficients of the regression analyses. This evidence concerns the gene APOE and Alzheimer disease.