TF and Sepsis: In the arterial system, “fibrin meshes” formed from activated TF path at the arterial vascular damage site (e.g., in hospital arterial access/device) travel to the tissue via efferent circulation into the peripheral microvasculature of the digits where they encounter “microthrombi strings” that have already been formed in the arterioles and capillaries of the sepsis-associated aEA-VMTD.