TF and deep vein thrombosis: Surgery, vascular access, vascular device, and ventilator support with tracheal intubation as well as incidental in-hospital trauma can lead to vascular wall damage, which unlike distal DVT can trigger “venous combined micro-macrothrombosis” characterized by laboratory data showing activated ULVWF path with increased release of ULVWF and FVIII and activated TF path with markedly elevated D-dimer.