CHMP5 and infection: The Omicron variant (B.1.1.529), with more than 30 changes in the spike protein, as well as in other parts of its sequence, is an example of this; its accelerated infection rate in the world suggests a high capacity to reinfect people who have recovered from other variants such as Delta or to infect individuals with three-dose vaccinations, showing its capacity to evade immune responses and generate clinical outcomes different from those of other variants [69,70,71].