Cervical and vulvar cancer cells can inhibit the maturation and function of DCs through the secretion of factors such as IL-6, prostaglandin E2 (PGE2), receptor activator of NF-KB ligand (RANKL), and indoleamine 2,3-dioxygenase (IDO) [72,73,74,75]. This evidence concerns the gene IL6 and vulva cancer.