In HPV-related cervical, vulvar, and penile (pre-)cancer, multiple immunohistochemistry (IHC) studies have shown that the expression of PD-1 on T-cells and PD-L1 on myeloid cells and tumor cells is common [71,84,120,121,122,123,124,125,126,127,128,129,130,131,132]. This evidence concerns the gene CD274 and cancer.