Cases of a missense mutation in FGA exon 4 c.391c.T>C (p.Ser131Pro in α chain without the signal peptide) associated with hypofibrinogenemia were reported in a Polish family by Mital et al. A 29-year-old male with lifelong bleeding tendency (trauma-induced bleeding, bleeding after dental care) developed enormous penile hematoma after penis correction surgery. Here, FGA is linked to Hypofibrinogenemia.