Findings derived from a large-scale translational study using multiple reaction monitoring MS showed that a panel of 16 proteins, of which 9 (including L-selectin, insulin-like growth factor-binding protein 3, coagulation factor X, serum paraoxonase/lactonase 3, thrombospondin-1, hyaluronan-binding protein 2, heparin cofactor 2, apolipoprotein B-100 and von Willebrand factor) were significant univariate predictors of TIA and could help to distinguish TIA from mimics [135]. The gene discussed is VWF; the disease is transient ischemic attack.